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Aleksandra Walczak (ENS Paris), Diversity and prediction of immune receptor repertoires
8 February 2018 | 13 h 30 min - 14 h 30 min
The recognition of pathogens relies on the diversity of immune receptor proteins. Recent experiments that sequence entire immune cell repertoires provide a new opportunity for quantitative insight into naturally occurring diversity and how it is generated. I will show how applying statistical inference to these recent experiments that sequence entire B and T-cell repertoires we can quantify the origins of diversity in these sequences and characterize selection acting on the somatic evolutionary process that leads to the observed receptor diversity. I will discuss these results from the theoretical perspective of optimal repertoires.
André Ariew (Professor or Philosophy, University of Missouri, USA), Darwin’s use of statistics to develop his theory of evolution7 February | 14 h 30 min - 16 h 00 min at Centre de Génomique Fonctionnelle, Salle de réunion Sud
- 17 February at Centre de Génomique Fonctionnelle, Salle de réunion Nord
Thomas Kirkwood (Newcastle University and University of Copenhagen) – Understanding Ageing: The Great Puzzle of Our Time17 February | 17 h 30 min - 19 h 00 min at Salle de conférence du Centre de génomique fonctionnelle